The two-car crash was reported at around 11 p.m. in front of 7640 Highway 29, south of Bottle Rock Road, according to the California Highway Patrol and radio reports.
Debris was spread all over the roadway, which blocked by the vehicles involved as well as arriving emergency vehicles, the CHP said. Kelseyville Fire, Lakeport Fire, CHP and sheriff’s deputies responded.
When firefighters arrived they found one of the vehicles on fire and one of the crash victims out of their vehicle.
The only vehicle description given initially was that of a black car that was involved, with no information given on the second vehicle.
Shortly after arrival a battalion chief reported that one person had died at the scene, with another person suffering from major injuries.
Incident command requested an air ambulance to transport a patient, with clear skies reported overhead. However, Central Dispatch indicated that REACH and CalStar declined to transport out of the county due to concerns about the weather.
A Kelseyville Fire ambulance transported a patient to Sutter Lakeside Hospital, arriving shortly before midnight, according to reports from the scene.
The roadway was reopened to one-way traffic at approximately 12:13 a.m., with the roadway completely cleared and open exactly one hour later, the CHP reported.
Firefighters were released from the scene at about 12:50 a.m., according to radio reports.
Names of the crash victims were not available early Monday morning.
E-mail Elizabeth Larson at