The crash was dispatched just after 6 p.m. on Highway 20 near the Dollar General in Nice.
The motorcycle was down, as was the rider, who was lying on the ground in the middle turning lane.
Firefighters at the scene said the road was blocked in both directions and they requested an air ambulance respond to meet them at Sutter Lakeside Hospital’s helipad.
The crash victim suffered major injuries and was flown out of the county for treatment, according to radio traffic and the California Highway Patrol’s online crash reports.
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